Who Dares Wins, indicated that the UK must rid itself of its "twisted grips" to be rejuvenated. He specifically criticized the current Mayor of London, Sadiq Khan, and Labour leader Sir Keir Starmer, suggesting that their leadership perpetuates division within the country, and hinted at a possible future in politics himself. This sparked speculation about his potential candidacy for an MP position or the London mayoral election.

Supporters on social media have shown enthusiasm for Middleton's political ambitions, with some suggesting he should run for Reform UK. The presenter has received both encouragement and scrutiny for his comments, particularly when he referred to London as one of the world's murder capitals. He has also defended his choice of the word "cleanse," clarifying that he is referring to a need to eradicate violent crime and ensure public safety, rather than implying any ethnic cleansing.

Middleton pointed out the alarming rates of harassment and vehicle theft in London, as well as the flaws within the Metropolitan Police. He stressed the importance of promoting Britain’s cultural heritage and values, asserting that London should reclaim its status as the "heartbeat" of the UK. Furthermore, he took a light-hearted approach to a typographical error he made regarding the "mayor," playfully alluding to a potential future title of "Major Mayor Middleton." Meanwhile, the current Mayor of London's office and the Metropolitan Police have not yet commented on Middleton's statements amidst growing criticism of their performance.